Preheat oven to 400°F.
In a medium saucepan, melt 4 Tbsp. of butter over medium heat. Whisk in flour until smooth. Gradually whisk in milk stirring constantly, 5 minutes or until thickened.
Stir in cheeses and green chiles until smooth. Salt and pepper to taste.
In a large casserole dish, add cheese and cooked pasta. Stir to combine. Bake for 20 minutes or until cheese is bubbling and edges are browned.
Meanwhile, melt remaining butter in a skillet over medium heat. Add breadcrumbs and toss until brown.
Microwave BBQ sauce in a microwave-safe bowl for 30 seconds. Toss brisket in warm BBQ sauce.
Top mac and cheese with bread crumbs and brisket.
Broil 3-5 minutes until the top is golden brown.
Inspired by B&D Icehouse
Nutrition information per serving (1/8 of recipe): Calories 740; Total fat 38g (Sat. fat 21g; Trans fat 1g); Cholest. 130mg; Sodium 820mg; Total Carb. 38g; Fiber 0g; Total Sugars 10g; Protein 37g; Vit D (0% DV); Calcium (35% DV); Iron (10% DV); Potas. (2%DV)